Iran's Supreme Leader Ayatollah Ali Khamenei has rejected US President Donald Trump's offer of unconditional talks to improve bilateral ties.
Washington reimposed the sanctions last week after pulling out of a 2015 international deal aimed at curbing Iran's nuclear program in return for an easing of economic sanctions. Trump has also threatened to penalise companies that continue to operate in Iran.
"I ban holding any talks with America... America never remains loyal to its promises in talks," said Khamenei, who has the final say on policy in the Islamic Republic.
"America's withdrawal from the nuclear deal is a clear proof that America cannot be trusted," state TV quoted Khamenei as telling a gathering attended by thousands of Iranians.
The sanctions target Iran's trade in gold and other precious metals, its purchases of US dollars and its car industry.
Washington had said Iran's only chance of avoiding the sanctions would be to accept Trump's offer to negotiate for a tougher nuclear deal. Iranian officials already rejected the offer but it is the first time Khamenei has publicly commented.
Khamenei, whose remarks on Monday come amid a sharp fall in the rial currency that has prompted angry protests, criticised the government of President Hassan Rouhani, a pragmatist cleric who championed the 2015 deal aimed at ending Iran's political and economic isolation.
"More than the sanctions, economic mismanagement (by the government) is putting pressure on ordinary Iranians... I do not call it betrayal but a huge mistake in management," state TV quoted Khamenei as saying.
"With better management and more efficient planning we can resist the sanctions and overcome them."
European countries, which still back the 2015 deal, fear Trump's moves will undermine Rouhani and strengthen the hand of his hardline rivals.
