Sanofi partners US Army on Zika vaccine

French pharmaceutical giant Sanofi is partnering with the US Army to speed up the development of a Zika vaccine.

An Aedes aegypti mosquito

Drugmaker Sanofi is partnering with the US Army to speed up the development of a Zika vaccine. (AAP)

French drugmaker Sanofi said on Wednesday it had struck a research and development deal with the US Army to speed up the development of a vaccine against the mosquito-borne Zika virus.

Sanofi is the only major drugmaker working on a vaccine against Zika, which has been linked to birth defects and neurological disorders, although more than a dozen smaller biotech firms and other groups are also active in the field.

The tie-up with the Walter Reed Army Institute of Research in the US gives Sanofi access to a promising new vaccine, made from inactivated virus, that has already produced impressive results in mice.

The vaccine is one of the furthest advanced in development and could be ready for testing on humans in October.

Sanofi said the Walter Reed Army Institute, a biomedical research facility administered by the US Department of Defense, would transfer virus vaccine technology to Sanofi Pasteur, the company's vaccines division.

The US National Institute of Allergy and Infectious Diseases will conduct the Phase I trials during the technology transfer and then Sanofi will be in charge of clinical and regulatory development.

Global health officials are racing to better understand the Zika virus, which has caused a major outbreak that began in Brazil last year and has spread to many countries in the Americas.

The World Health Organisation has said there is strong scientific consensus that Zika is a cause of the birth defect microcephaly, or small heads in babies, as well as Guillain-Barre syndrome, a neurological disorder.

A single dose of the Walter Reed Army Institute's experimental vaccine was shown to give 100 per cent protection in mice against the Zika virus, according to a study published in Nature last week, boosting hopes that it will also work in humans.

Sanofi is developing another Zika vaccine based on its own know-how in battling established mosquito-borne diseases such as dengue, Japanese encephalitis and yellow fever.

However, that vaccine will take longer to develop and Sanofi said earlier this year it did not expect to start clinical trials on its in-house Zika candidate until 2017.


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Published 6 July 2016 7:22pm
Source: AAP


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